Topical Dutasteride

1) Each XYON bottle has a safety lock. Turn the safety lock to the open position and press down once to dispense a pre-measured amount of treatment.

2) Focus application of the treatment on affected areas of the scalp. You may need to part your hair. Rub the gel in for 20-30 seconds.

3) You're done. You can style your hair as usual. Ensure that you wash your hands with soap and warm water after applying and/or touching the gel.

Make sure to follow the dosing instructions indicated in your prescription. We usually recommend applying the gel first thing in the morning and leaving it on for approximately 8 hours. Avoid applying before bed to avoid transferring the treatment to pillows and/or sheets.

Missed a dose? Resume regular application as soon as possible. It's important not to double up on missed doses.

It's not uncommon for people to notice some increased shedding in the first few weeks/months after starting a new hair loss treatment. This should go away with time, but if this shedding doesn't stop or worsens, you should notify your prescribing doctor.

Clinical studies have shown that oral dutasteride is an effective medication when it comes to treating male pattern hair loss. Although additional data is needed, preliminary trials on topical formulations of 5-alpha reductase inhibitors like dutasteride suggest that effectiveness is comparable. In XYON's own clinical studies, all study participants experienced at least some improvement in their hair loss while taking topical dutasteride.

It's important to understand that individuals can lose hair for various reasons and treatment options depend on the type of hair loss. Patients experiencing traction alopecia, scarring alopecia, or telogen effluvium should consult a dermatologist to determine their best treatment options. Topical Dutasteride, with SiloxysSystem™ Gel does not treat these hair loss conditions.

It can take several months of consistent treatment with topical dutasteride (3-6 months or more) before seeing noticeable improvements in male pattern baldness.

This timeframe can vary depending on individual factors such as age, genetics, and coexisting medical conditions. Consistent application can help maximize results.

Topical Dutasteride, with SiloxysSystem™ Gel treats hair loss by addressing the main hormonal cause of male pattern baldness. It works by blocking the activity of type 1 and 2 isozymes of the 5 alpha-reductase enzyme. This prevents the conversion of testosterone to dihydrotestosterone (DHT), the main hormone linked to male pattern baldness and some cases of female pattern hair loss.

This treatment may help slow down or stop further hair loss and helps promote the regrowth of existing hairs.

Unlike other hair loss solutions, Topical Dutasteride, with SiloxysSystem™ Gel may also help lower the risk of systemic side effects by limiting absorption of dutasteride into the body. It may be a good option for people who are concerned about side effects.

SiloxysSystem™ is a patented gel delivery system that has been uniquely developed to help target the delivery of clinically-proven hair loss treatments to the scalp layer containing hair follicles.

It's also been formulated to administer medications over time. By helping reduce absorption and controlling delivery, the gel is intended to help lower the risk of potential side effects.

We often receive questions about the safety of the concentration of dutasteride in our topical formulations. This is a great and important question.

Our compounded topical formulations contain 2% dutasteride. Since topical dutasteride is used even less frequently than topical finasteride, there is no standard concentration or dosing frequency. To understand why this concentration was chosen, we can start by understanding the factors that impact the potency, or strength of dutasteride.

The amount of dutasteride in a formulation is one factor. The other is the vehicle, or the base in which dutasteride is being compounded. This can affect the ability of the medication to penetrate the skin.

Dr. Hasson has made SiloxysSystem™ Gel available after years of clinical experience using the vehicle in his own patients as a way to help reduce side effects. The gel combines silicone with delivery molecules called liposomes to help reduce systemic absorption. 2% dutasteride was ultimately selected because it strikes a balance between safety and efficacy. You can learn more about how this technology helps reduce systemic absorption by viewing our clinical study: Topical Dutasteride Clinical Study Results.

Topical dutasteride can be used with other hair loss treatments, but you may need to consider the order of application and whether dutasteride may cause a drug interaction. Certain drugs and hormonal therapies should be avoided when taking dutasteride. When in doubt, you should always consult with a doctor.

The side effects of topical dutasteride are similar to the oral medication. In general, side effects are less common with topical formulations.

The side effects of oral dutasteride include erectile dysfunction, decreased libido (sex drive), ejaculatory disorders and breast swelling and/or tenderness.

Additional side effects associated with topical formulations include irritation near the site of application. These are typically mild.

Talk to your doctor before starting topical dutasteride treatment to ensure that you don't have any medical conditions that may affect the likelihood of developing an adverse reaction to dutasteride.

You can learn more about dutasteride side effects by visiting our medical library.

Compounded hair loss medications are customized topical treatments prepared by a pharmacist specifically for a patient.

The pharmacist expertly combines medications into a topical base, which allows patients to apply them directly to the scalp. It's a way of personalizing treatment because it considers medical history, lifestyle, age and other factors.

Remember, compounded treatments are not FDA-approved and require a doctor’s prescription. You will need to consult with a doctor to determine if such a treatment is right for you.

We often get asked about the dosage of dutasteride in our compounded hair loss treatments. The concentration of a medication that can be safely mixed into a treatment depends on several factors, including the properties of the base. Since SiloxysSystem™ Gel was specifically developed to help control and reduce absorption of ingredients into the body, the concentration of dutasteride may be higher in order to achieve the desired clinical result.

Topical dutasteride from XYON is available in the United States and Canada exclusively through xyonhealth.com. Enter XYON's secure online platform to start a consultation to get access to a prescription.