XYON’s digital health platform connects you with a specialist dermatologist who will assess your individual case to determine which, if any, of the following treatments and innovative formulations, including FDA-approved oral finasteride and SiloxysSystem™ gel, would be appropriate for you and your hair loss.

Topical Finasteride, with SiloxysSystem™ Gel

Topical Finasteride, with SiloxysSystem™ Gel is a compounded topical medicine designed to target androgenetic hair loss at the scalp.

SiloxysSystem™ gel was formulated to deliver medications such as finasteride to the layer of scalp skin containing hair follicles with a high degree of precision.

Compounded with finasteride at up to 2.5%, this innovative topical carrier is designed to maximize drug action at the hair follicle and minimize systemic absorption into the bloodstream. This may potentially reduce the incidence of side effects associated with the oral version of the medication.

Topical Dutasteride, with SiloxysSystem™ Gel

Topical Dutasteride, with SiloxysSystem™ Gel is a compounded topical medicine designed to target androgenetic hair loss at the scalp.

SiloxysSystem™ gel was formulated to deliver medications such as dutasteride to the layer of scalp skin containing hair follicles with a high degree of precision.

Compounded with dutasteride at up to 2.0%, this innovative topical carrier is designed to maximize drug action at the hair follicle and minimize systemic absorption into the bloodstream. This may potentially reduce the incidence of side effects associated with the oral version of the medication.

Oral finasteride

Oral finasteride is generally a safe and effective treatment indicated and FDA-approved for men with male pattern hair loss. It is often the first-line treatment for men who do not suffer from, or are not concerned about side effects from oral finasteride. These side effects include erectile dysfunction and low libido.

Dutasteride and finasteride both target the same family of enzymes (5-alpha reductases, 5-ARs) that is responsible for processing of the hormones (testosterone to dihydrotestosterone (DHT)) in the scalp associated with hair loss. While finasteride blocks one target from this family, dutasteride blocks two. Topical dutasteride, therefore, results in a more dramatic reduction in the hormones associated with hair loss in the scalp than topical finasteride.

Each medication available through the XYON platform requires a consultation from a specialist dermatologist and a valid prescription, all available through www.xyonhealth.com. Our licensed medical professionals consider a variety of factors before determining which medical treatment and drug dosage is right for you. There is no one-size-fits-all treatment for androgenetic hair loss.

Start a consultation with a specialist dermatologist to discuss your treatment options.

Oral Finasteride

Oral finasteride is FDA-approved to treat male pattern hair loss at 1 mg/day.

Topical Finasteride with SiloxysSystem™ Gel

Topical finasteride is currently not approved by the FDA as a treatment for male pattern hair loss in any form or concentration.

Any topical formulation containing finasteride is considered a compounded medicine. Compounded medicines contain FDA-approved drugs in forms, concentrations, combinations or indications that have not been individually approved. These customized formulations are tailored to the individual needs of patients. They may be appropriate in cases where patients have experienced side effects while taking the FDA-approved version of the drug, or if patients are concerned about the risk of side effects.

Compounded drugs such as topical finasteride must be prescribed by a licensed physician and can only be dispensed by a compounding pharmacy registered in the province or state in which you reside.

Topical Dutasteride with SiloxysSystem™ Gel

Topical dutasteride is currently not approved by the FDA as a treatment for male pattern hair loss in any form or concentration.

In the United States, oral dutasteride is only authorized to treat a medical condition called benign prostatic hyperplasia (BPH) at a dosage of 0.5 mg/day. Alternate forms, dosages, or indications of this drug are considered to be compounded medicines and are not endorsed by the FDA.

Compounded medicines contain FDA-approved drugs in formulations that have not been individually evaluated for long-term safety and efficacy. Compounded drugs such as topical dutasteride must be prescribed by a licensed physician and can only be dispensed by a compounding pharmacy registered in the province or state in which you reside.

Compounded medicines are tailored to the individual needs of each patient. These customized formulations may be appropriate in cases where patients have experienced side effects while taking the FDA-approved version of the drug, or if patients are concerned about the risk of side effects. The prescribing dermatologist should review your health history and address your concerns before determining the most suitable treatment for your hair loss.

XYON’s exclusive compounding medium, SiloxysSystem™ gel, is produced by manufacturers in North America and Europe who follow Good Manufacturing Practices (GMP). The active ingredients (ie. finasteride or dutasteride) are compounded with SiloxysSystem™ gel by a leading compounding pharmacy in the United States, according to each individual prescription.

Oral hair growth treatments are absorbed at the level of the gut and circulate through the bloodstream, reducing the overall concentration of a hormone called dihydrotestosterone (DHT) throughout the body. While effective at targeting hair loss, oral hair growth treatments may carry a greater risk of side effects such as decreased libido or erectile dysfunction because of its widespread effect on DHT.

Topical finasteride and dutasteride formulations maximize drug action at the hair follicle and minimize drug action through the rest of the body, potentially lowering the risk of side effects. These may be appropriate for men who have experienced sexual or other side effects while taking oral hair growth treatments, or in men who may have sexual symptoms without using finasteride or dutasteride. A recent literature review found topical finasteride treatments to be equally as effective as oral finasteride in improving hair density and quality in men with androgenetic alopecia (AGA) with less of an impact on serum DHT (Lee et a. 2018). Pharmacokinetic (PK) data comparing compounded Topical Finasteride, with SiloxysSystem™ Gel and the FDA-approved oral finasteride dosage can be found in this article.

You should apply the amount recommended by the prescribing dermatologist which is often one pump of the gel to your scalp each morning. One pump a day is recommended to see the clinical efficacy that Dr. Hasson has demonstrated. However, the dermatologist involved in your consultation will ultimately decide on the appropriate dosing for you based on your clinical photographs and medical history.

If you have questions about application of the treatment, please refer to the drug fact sheet included with your prescription, or talk to the prescribing dermatologist.

Find out more about the results of patients using one pump daily of Topical Finasteride, with SiloxysSystem™ Gel here.

After application of the topical treatment to your scalp it is recommended to wait for a minimum of 4 hours. If you would like to apply any styling products to your hair, that can be done immediately after applying the gel to your scalp.

If you are experiencing any side effects cease usage of the treatment and seek medical attention immediately.

Any side effects that you believe to be associated with your prescription should be reported to the prescribing dermatologist and the dispensing pharmacy.

Shortness of breath, chest pain, nausea/vomiting or loss of consciousness may indicate a severe allergic reaction otherwise known as anaphylaxis. You should seek medical attention urgently if you experience any of these symptoms.

All medicines have the potential to cause side effects. However, many people have no side effects or only experience minor side effects while taking finasteride or dutasteride in any form, including oral or topical.

The following side effects are most frequently associated with finasteride and dutasteride: feeling tired or weak, lowered interest in sex, ejaculation problems, trouble getting or keeping an erection, breast enlargement or tenderness.

While rare, side effects may persist even after you have stopped using topical finasteride or dutasteride. Follow up with the prescribing dermatologist if these symptoms do not subside or persist even after you have discontinued treatment.

Consistent application of any topical medication for at least 9-12 months is recommended to assess efficacy. Male pattern hair loss is a progressive condition that worsens over time without any treatment. Therefore, the success of treatment should be evaluated in two ways: the maintenance of existing hairs and the growth of new hairs. Both are considered a sign of success with any hair loss treatment.

Additionally, it is normal to have some degree of hair shedding in the early phase of treatment (within the first 1-2 months). With continued treatment, this should decrease as older hairs are pushed out to make way for new hair growth.

If you have any questions or concerns about persistent or excessive hair loss after starting your treatment, please reach out to your prescribing dermatologist.

You will have to complete the consultation process through xyonhealth.com to start your hair growth journey with XYON. Your new and current prescription is needed to switch to compounded Topical Finasteride or Topical Dutasteride, with SiloxysSystem™ Gel, or oral finasteride through XYON’s online platform.

Once you have completed your online profile, an independent specialist dermatologist will review your application within 2 business days and determine which treatment is most suitable for your hair loss. They will let you know if you have been approved for a prescription and provide you with the next steps.

All treatments offered through XYON subscriptions are not covered by public health insurance plans. If you have private health coverage, please check with your provider.

To determine the right hair growth treatment for you, begin your free consultation with a board-certified dermatologist

Topical Finasteride, with SiloxysSystem™ Gel, and Topical Dutasteride, with SiloxysSystem™ Gel are compounded medicines that can only be obtained through xyonhealth.com. Any medication compounded with SiloxysSystem™ gel requires a valid prescription from an independent dermatologist.

Before discontinuing your current treatment, you should consult with the prescribing dermatologist to discuss beginning a new treatment for your hair loss.

If you are issued a new prescription for a different medication, you can cancel your current subscription and begin the alternate treatment prescribed to you.

If you have obtained a new prescription and would like to cancel your current medical subscription, please reach out to XYON’s Customer Experience Team at [email protected].