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With any pharmaceutical drug, there is always a risk that you may experience adverse reactions. The risk of experiencing adverse drug reactions to topical finasteride is typically considered to be lower than the risk associated with oral treatment. This is related to higher circulating finasteride levels in the bloodstream which in turn can cause unwanted side effects, such as sexual dysfunction with oral finasteride. A topical delivery system, such as the Topical Finasteride, with SiloxysSystem™ Gel, can help reduce systemic exposure to the medication, minimizing the risk of associated sexual side effects. It is important to note however, that not all topical formulations are designed to do this. SiloxysSystem™ was specifically designed to reduce systemic exposure of active medicines such as finasteride.
The most common adverse effects observed with topical medicines of any kind are skin reactions such as redness, itching or peeling. If your sexual health has been negatively affected by topical finasteride treatment, the effects are usually temporary and should resolve once treatment has been discontinued.
You should speak with your physician if you are concerned about the side effect profile of finasteride or experience any skin or other changes after starting oral or topical finasteride.
Oral finasteride treatments are absorbed at the level of the gut and circulate through the bloodstream, reducing the overall concentration of a hormone called dihydrotestosterone (DHT) throughout the body. While effective at targeting hair loss, oral finasteride carries a greater risk of side effects such as decreased libido or erectile dysfunction because of its effect on DHT widely in the body.
Topical finasteride formulations may reduce drug action throughout the body and therefore lower the risk of side effects. These may be useful therefore in men with sexual or other side effects who use oral finasteride, or in men who may have sexual symptoms without using finasteride. A recent literature review found topical finasteride treatments to be equally as effective as oral finasteride in improving hair density and quality in men with androgenetic alopecia (AGA) with less of an impact on serum DHT.
To determine if you are a good candidate for topical finasteride, it’s recommended that you consult with a doctor. XYON offers access through its platform to leading independent certified dermatologists who can assess your hair loss and review your medical history. These dermatologists will decide what the best treatment for you might be.
Topical finasteride reduces levels of dihydrotestosterone (DHT), which is effective at treating many types of hair loss, including androgenetic alopecia. A dermatologist will be able to determine which hair loss treatment is best suited for you.
Hair loss resulting from other conditions, medical treatments or procedures, nutritional deficiencies or for any other known reason, should not necessarily be treated with topical finasteride. You should always consult with a doctor to determine the cause of your hair loss and discuss the right treatment option for you.
Most often, medications used to treat androgenetic alopecia (AGA) improve hair quality and typically increase the number of mature hairs at the scalp. In certain cases, hair loss is not entirely reversible, but hair should appear thicker and healthier with consistent, daily finasteride use. Starting topical finasteride as early as possible after noticing hair loss is the most effective way of slowing down or stopping future hair loss.
This is normal and indicates that the medication is working. If your hair loss has increased since starting treatment with topical finasteride, you are probably experiencing shedding. Shedding occurs when one hair growth cycle is terminated and mature hairs are lost. This initial hair loss indicates that new growth can occur from active follicles and a hair growth cycle has begun.
Shedding generally stops within three to six months. If your hair loss persists beyond six months after starting treatment with topical (or oral) finasteride, it’s important that you consult with a physician.
Consistent application and continued use of topical finasteride are required to reduce DHT concentrations at the scalp and effectively target androgenetic hair loss. The benefits of topical finasteride will not last once treatment has stopped, so treatment is required over the longer term. In most cases, daily application will yield the best results.
Continued use of topical finasteride is necessary to maintain hair regrowth that has occurred since beginning treatment and to prevent further hair loss. Once you have stopped using topical finasteride, you can expect your hair to return to its original state prior to starting treatment. You may also experience additional hair loss without active treatment.
Topical Finasteride, with SiloxysSystem™ Gel is easily absorbed, does not leave a greasy film on the skin and does not have a strong scent, so application is typically not noticeable at all. The effects of topical finasteride treatment on hair count and quality occur gradually and those around you will therefore not see a drastic change overnight. This is often deemed a highly desirable feature of the Topical Finasteride, with SiloxysSystem™ Gel.
While interactions between topical finasteride and other drugs have not been extensively studied, there are no known and no suspected drug interactions of clinical significance associated with the use of Topical Finasteride, with SiloxysSystem™ Gel. The reason is that the systemic absorption of finasteride into the body is so low that it is unlikely for finasteride to interact with other medicines in the body in a meaningful manner.
Topical finasteride should not be used if:
- You are living with a pregnant woman
- You have known allergies to or had previous adverse reactions when using finasteride
- You have been diagnosed with or are suspected of having prostate cancer
Both oral and topical finasteride should be used with caution in situations where a woman at home is trying to conceive or breastfeeding. Finasteride is potentially harmful to a developing fetus, so should be kept away from a woman in the above settings where contamination might be harmful. This includes skin, oral or vaginal contamination.
It is important to inform the dermatologist or pharmacist if your partner or a woman you live with is pregnant, trying to conceive or is breastfeeding.
You should disclose a complete and current list of supplements, prescription medications and over-the-counter drugs you take on a regular basis to the prescribing physician.
Finasteride is the most clinically effective medication used to treat androgenetic alopecia (AGA). The Topical Finasteride, with SiloxysSystem™ Gel formulation available through XYON has been tested by Dr. Victor Hasson and shown alone to be highly effective in the prevention and treatment of AGA, and to be very well tolerated. However, some patients may choose to take multiple treatments simultaneously. It is important to speak to the prescribing dermatologist to ensure it is appropriate to combine multiple treatments.
Yes, you can use topical finasteride after a hair transplant. However, it is recommended that you consult with a hair restoration specialist, physician or dermatologist to determine how soon after surgery, medical treatment is appropriate and which drug formulation is most suitable following your medical procedure.
Finasteride is currently FDA-approved to treat androgenetic alopecia (AGA) at a dosage of 1mg/day administered orally.
Topical finasteride has not been approved by the FDA in the treatment of AGA and is a compounded medicine used typically in situations where the approved FDA form is not suitable. Topical formulations containing finasteride must be prescribed by a licensed physician and can only be produced by a compounding pharmacy registered in the state or province you reside.
You should only apply topical finasteride to the scalp and use in other areas of the body is not recommended as it has not been tested in such areas. Topical finasteride treatments were formulated to target hair loss at the scalp by reducing local levels of dihydrotestosterone (DHT). A reduction in DHT is not known to stimulate hair growth at any site other than the scalp.
Topical finasteride is generally safe for biological males undergoing hormone replacement therapy. However, because finasteride impacts a hormone called dihydrotestosterone (DHT), it is important you disclose to your doctor if you are on HRT to ensure that they can make an informed and unbiased decision when prescribing topical finasteride.
If you are undergoing hormone therapy as a treatment for prostate cancer you should not use finasteride in any form.
If you are experiencing acute adverse side effects from any drug, seek medical attention immediately.
Shortness of breath, chest pain, nausea/vomiting or loss of consciousness may indicate a severe allergic reaction otherwise known as anaphylaxis (Source: NIH). If you are experiencing any of these symptoms after using the Topical Finasteride, with SiloxysSystem™ Gel, seek medical attention immediately or call 9-1-1.
Any complications or adverse reactions to Topical Finasteride, with SiloxysSystem™ Gel should be reported to your dermatologist and pharmacy.